Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)

The purpose of this notice of funding opportunity (NOFO) is to support a consortium of Translational Centers using Microphysiological Systems (MPS) for Infectious Diseases (TCMID). Recent efforts in the MPS fields are moving towards validation and regulatory use but have not focused upon models stud…

Closes 29 Jan 2027 (86 days)

up to USD 7,000,000. National Institutes of Health

Open the application page

Who can apply

Where
United States, nationwide
Industries
any, or not stated
Business size
not stated
Amount
up to USD 7,000,000
Dates
opens 20 Oct 2026; closes 29 Jan 2027

The funder's text has not been read for criteria yet; open the source for the full rules.

Eligibility, in the funder's words

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

National Institutes of Health, source

About the program

The purpose of this notice of funding opportunity (NOFO) is to support a consortium of Translational Centers using Microphysiological Systems (MPS) for Infectious Diseases (TCMID). Recent efforts in the MPS fields are moving towards validation and regulatory use but have not focused upon models studying infectious diseases and testing of medical interventions. The NIH and FDA have recently issued guidance and established initiatives for enhancing use of New Approach Methodologies (NAMs) in research and product development. This includes in vitro systems that allow scientists to model human disease and capture human variability and patient-specific characteristics that will accelerate safer treatments for patients while reducing costs and sparing use of laboratory animals. To meet this need, the Centers will refine well validated human tissue models studying infectious diseases to a level consistent with regulatory qualifications that will promote their adoption for use by product developers, supporting regulatory acceptance.

Common questions

Am I eligible?

Only National Institutes of Health can say. The rules above are what the notice states; sign in and your business profile is compared with them line by line for a likely, maybe or unlikely verdict.

When does it close?

29 Jan 2027. Save it in your account for reminders 14, 7 and 2 days before.

Where do I apply?

On the funder's page: https://www.grants.gov/search-results-detail/362954

Is this one for you?

Sign in and your state, industry, size and turnover are compared with these rules line by line. Save it for closing reminders.