Assessing the Feasibility of Incorporating Mechanisms in Multi-site Clinical Trials of Mind and Body Interventions on Whole Person Health Restoration (R33 Clinical Trial Required)
The National Center for Complementary and Integrative Health (NCCIH) announces this Notice of Funding Opportunity (NOFO) to solicit applications for multi-site feasibility trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mi…
Closes 16 Nov 2029 (1108 days)
up to USD 500,000. National Institutes of Health
Who can apply
- Where
- United States, nationwide
- Industries
- any, or not stated
- Business size
- not stated
- Amount
- up to USD 500,000
- Dates
- opens 15 Oct 2026; closes 16 Nov 2029
The funder's text has not been read for criteria yet; open the source for the full rules.
Eligibility, in the funder's words
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
About the program
The National Center for Complementary and Integrative Health (NCCIH) announces this Notice of Funding Opportunity (NOFO) to solicit applications for multi-site feasibility trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) to reproduce and translate mechanisms of emotional well-being (EWB) into large-scale clinical trials that advance our understanding of whole person health. These early-phase multi-site trials are essential for 1) demonstrating that the mind and body intervention can be delivered with fidelity across sites; 2) demonstrating reproducibility and rigor in engaging targeted mechanisms of EWB by the mind and body intervention across sites; 3) assessing feasibility of participant recruitment and retention, as well as randomization; 4) assessing feasibility of collecting comprehensive clinical (whole person health restoration) and mechanistic (EWB) data across sites; and 5) exploring correlations between changes in mechanistic targets and clinical outcome measurements pooled across sites. By laying this groundwork, studies supported under this NOFO will advance the science of whole person health and prepare the field for rigorous clinical trials and mechanistic mediation analysis with the potential to improve the health and well-being of all Americans.
Common questions
Am I eligible?
Only National Institutes of Health can say. The rules above are what the notice states; sign in and your business profile is compared with them line by line for a likely, maybe or unlikely verdict.
When does it close?
16 Nov 2029. Save it in your account for reminders 14, 7 and 2 days before.
Where do I apply?
On the funder's page: https://www.grants.gov/search-results-detail/359941
Is this one for you?
Sign in and your state, industry, size and turnover are compared with these rules line by line. Save it for closing reminders.